The city of Kansas City, Kansas, currently has 8 active clinical trials seeking participants for Pain research studies.
Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
NCT03854344
Recruiting
Donor site pain study comparing post-operative donor site pain and opioid consumption after use of Lidocaine, Liposomal Bupivicaine or regional nerve block for split thickness skin graft harvesting in patients with less than 20% TBSA burn wounds and less than %5 Deep partial or full thickness burn wounds.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: The University of Kansas Health System, Kansas City, Kansas
Conditions: Pain, Postoperative, Burns
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
All
Ages:
Between 0 years and 20 years
Trial Updated:
03/29/2024
Locations: University of Kansas Medical Center-JG Kidney Institute, Kansas City, Kansas
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
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Trial Readiness and Endpoint Assessment in LGMD R1
NCT05618080
Recruiting
This is a 24-month, observational study of 100 participants with Limb Girdle Muscular Dystrophy type R1, also known as CAPN3.
Gender:
All
Ages:
Between 12 years and 50 years
Trial Updated:
02/01/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A, Limb Girdle Muscular Dystrophy, Limb Girdle Muscular Dystrophy Type R1, LGMD2A
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Chronic Pain, Opioid Use, and Epidermal Nerve Fiber Density
NCT04801498
Recruiting
This pilot study is being performed to examine whether epidermal axons are altered in patients taking opioid therapy for chronic non-cancer pain, and if epidermal axonal changes predict heightened pain sensitivity.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
12/01/2023
Locations: University of Kansas Health System, Kansas City, Kansas
Conditions: Chronic Pain, Opioid Use, Nerve Disorders
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Quantify the Degree of Pain Relief of Pelvic Congestion Syndrome Following Gonadal Vein Embolization
NCT03794466
Recruiting
The primary objective is to quantify the degree of pain relief in patients undergoing gonadal vein embolization with coils as well as identify clinical or imaging factors that are predictive of a positive response to treatment, or poor response to treatment.
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/28/2023
Locations: The University of Kansas Medical Center, Kansas City, Kansas
Conditions: Pelvic Congestive Syndrome, Pelvic Pain
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Improving Pain Management Via Spinal Cord Stimulation and Blood Pressure Reduction
NCT04676399
Recruiting
The purpose of this study (PASSION study) is to monitor symptoms of chronic pain before and after 2 weeks of a standard drug commonly used to treat elevated blood pressure compared with 2 weeks of placebo (crossover design) so that we may better understand how blood pressure affects your level of pain. This study is not testing an experimental drug.
Gender:
All
Ages:
Between 40 years and 79 years
Trial Updated:
02/08/2022
Locations: The Marc A. Asher Comprehensive Spine Center at the Kansas University Medical Center, Kansas City, Kansas
Conditions: Chronic Pain, Hypertension, Diuretics Drug Reactions, SCS
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Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.
NCT04730700
Recruiting
The purpose of this study is to better understand how people feel after a radiofrequency ablation standard of care surgery using a different type of needle (multi-tined expandable electrode/MEE) in comparison to receiving conventional medical management (CMM) techniques.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Chronic Low-back Pain
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Epidural Spinal Cord Stimulation for Hypertension in Patients With Neuropathic Pain
NCT04598035
Recruiting
The purpose of the ESCAPE Study is to determine the extent to which epidural spinal cord stimulation (SCS) reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension. We also aim to determine the extent to which higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS implant. This is an observational study of patients undergoing an implantation of a SCS device.
Gender:
All
Ages:
Between 30 years and 89 years
Trial Updated:
01/28/2021
Locations: The Marc A. Asher Comprehensive Spine Center at the Kansas University Medical Center, Kansas City, Kansas
Conditions: Chronic Pain, Hypertension, Implanted Stimulation Electrodes
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